Circadian 5-HT production regulated by adrenergic signaling
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چکیده
منابع مشابه
Circadian 5-HT production regulated by adrenergic signaling.
Using on-line microdialysis, we have characterized in vivo dynamics of pineal 5-hydroxytryptamine (5-HT; serotonin) release. Daily pineal 5-HT output is triphasic: (i) 5-HT levels are constant and high during the day; (ii) early in the night, there is a novel sharp rise in 5-HT synthesis and release, which precedes the nocturnal rise in melatonin synthesis; and (iii) late in the night, levels a...
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In the human adrenal cortex, serotonin (5-HT) is contained in mast-like cells, and we have shown that 5-HT stimulates aldosterone secretion, suggesting that 5-HT may control glomerulosa cells through a paracrine mechanism. Concurrently, the presence of 5-hydroxyindolacetic acid in human adrenocortical extracts indicates that 5-HT may be metabolized after local release by mast cells. The aim of ...
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Motoneuron excitability and muscle spasms are regulated by 1 5-HT2B and 5-HT2C receptor activity. 2 3 Katherine C. Murray, Marilee J. Stephens, Edmund W. Ballou, Charles J. Heckman, 4 and David J. Bennett 5 Centre for Neuroscience, University of Alberta, Edmonton, Alberta, Canada; Department of Physiology, 6 Northwestern University, Chicago, IL, USA. 7 8 9 Running Title: 5-HT2B receptors on mot...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.062585499